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ba0001pp162 | Cancer and bone: basic, translational and clinical | ECTS2013

Effect of zoledronic acid on bone metabolism in patients with bone metastases from prostate or breast cancer: the ZOTECT Study

Hadji Peyman , Ziller May , Maurer Tobias , Autenrieth Michael , Muth Mathias , Ruebel Amelie , May Christoph , Birkholz Katrin , Diebel Erhardt , Gleissneer Jochen , Rothe Peter , Gschwend Juergen E

Introduction: The prospective, single-arm, open-label ZOTECT study was designed to assess the effect of zoledronic acid (ZOL) on bone-marker levels and potential correlations with disease outcomes in bisphosphonate-naive patients with bone metastases.Methods: Patients with bone metastases from prostate cancer (PC; n=301) or breast cancer (BC; n=99) who have not received bisphosphonates for ≥6 months were enrolled at 98 sites in Ge...

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Effect of zoledronic acid on bone metabolism in patients with bone metastases from prostate or breast cancer: the ZOTECT Study

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